Journal article
Part 2: Making the “unproven” “proven"
Cytotherapy, Vol.18(1), pp.120-123
2016
Abstract
The use of living, disaggregated cells in medicine involves a number of aspects that make this approach distinct from traditional pharmaceutical products. Cells are not metabolized by the liver or kidney, unlike most small-molecule drugs, but are potentially capable of distribution throughout the entire body. Cells are also highly complex and change dynamically in response to their environment and over time, making it difficult to standardize them in the same way that molecules can be engineered and mass-produced. Some type of cells may also secrete multiple bioactive molecules, such as cytokines and growth factors, as well as microvesicles, which may be released in different amounts or combinations, depending upon the cells' immediate environment or the pathophysiological state of the body into which they are introduced...
Details
- Title
- Part 2: Making the “unproven” “proven"
- Authors/Creators
- D.J. Weiss (Author/Creator) - University of VermontJ.E.J. Rasko (Author/Creator) - The University of SydneyN. Cuende (Author/Creator) - Regional Government of AndalusiaM.A. Ruiz (Author/Creator) - Bone Marrow Transplantation and Cell Therapy Unit, Associação Portuguesa de Beneficencia, SJ Rio Preto, Sao Paulo, Brazil. ISCT South & Central America, Past Regional Vice President 2013–2015H-N Ho (Author/Creator) - National Taiwan UniversityR. Nordon (Author/Creator) - UNSW SydneyS. Wilton (Author/Creator) - The University of Western AustraliaM. Dominici (Author/Creator) - University of Modena and Reggio EmiliaA. Srivastava (Author/Creator) - Christian Medical College, Vellore
- Publication Details
- Cytotherapy, Vol.18(1), pp.120-123
- Publisher
- Elsevier BV
- Identifiers
- 991005544887607891
- Copyright
- © 2015 International Society for Cellular Therapy
- Murdoch Affiliation
- Centre for Comparative Genomics
- Language
- English
- Resource Type
- Journal article
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Source: InCites
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- Collaboration types
- Domestic collaboration
- International collaboration
- Citation topics
- 1 Clinical & Life Sciences
- 1.102 Stem Cell Research
- 1.102.110 Mesenchymal Stem Cells
- Web Of Science research areas
- Biotechnology & Applied Microbiology
- Cell & Tissue Engineering
- Cell Biology
- Hematology
- Medicine, Research & Experimental
- ESI research areas
- Biology & Biochemistry