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Pathogenesis and molecular biology of a transmissible tumor in the Tasmanian devil
Journal article   Peer reviewed

Pathogenesis and molecular biology of a transmissible tumor in the Tasmanian devil

H.S. Bender, J.A. Marshall Graves and J.E. Deakin
Annual Review of Animal Biosciences, Vol.2(1), pp.165-187
2014
DOI: https://doi.org/10.1146/annurev-animal-022513-114204
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Abstract

The emergence of a fatal transmissible cancer known as devil facial tumor disease (DFTD) is threatening the iconic Tasmanian devil with extinction in the wild within the next few decades. Since the first report of the disease in 1996, DFTD has spread to over 85% of the devils’ distribution and dramatically reduced devil numbers. Research into DFTD has focused on gaining a deeper understanding of the disease on multiple levels, including an accurate assessment of the tissue origin of the tumor, elucidation of how the tumor evades immune detection, and determination of how the tumor is transmitted between individuals and how it is evolving as it spreads through the population. Knowledge gained from these studies has important implications for DFTD management and devil conservation.

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UN Sustainable Development Goals (SDGs)

This output has contributed to the advancement of the following goals:

#3 Good Health and Well-Being

Source: InCites

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37 Record Views
16 Times Cited - Web of Science

InCites Highlights

These are selected metrics from InCites Benchmarking & Analytics tool, related to this output

Collaboration types
Domestic collaboration
Citation topics
3 Agriculture, Environment & Ecology
3.232 Veterinary Sciences
3.232.1120 Veterinary Oncology
Web Of Science research areas
Biotechnology & Applied Microbiology
Veterinary Sciences
Zoology
ESI research areas
Plant & Animal Science
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