Journal article
Patterns of muscle Fiber-Type disproportion in hypotonic infants
Archives of Neurology, Vol.41(1), pp.53-57
1984
Abstract
We studied the histochemical characteristics of muscle in five hypotonic infants. A number of different patterns of disproportion in the sizes and numbers of type 1 and type 2 fibers were found. In three cases, type 1 fibers were smaller than type 2 fibers and type 2b or 2c fibers were largest. In one case, type 2 fibers were smaller than type 1 fibers and were reduced in number, while in a case of Prader-Willi syndrome there was a pre-ponderance of type 2 fibers that were smaller than type 1 fibers. Type 2c fibers were increased in number in all but one case. We postulate that these various patterns of fiber-type disproportion are the result of altered neural influences leading to impaired maturation of type 1 or type 2 motor units.
Details
- Title
- Patterns of muscle Fiber-Type disproportion in hypotonic infants
- Authors/Creators
- Z. Argov (Author/Creator)D. Gardner-Medwin (Author/Creator)M.A. Johnson (Author/Creator)F.L. Mastaglia (Author/Creator)
- Publication Details
- Archives of Neurology, Vol.41(1), pp.53-57
- Publisher
- American Medical Association
- Identifiers
- 991005540608107891
- Copyright
- © 1984 American Medical Association
- Murdoch Affiliation
- Murdoch University
- Language
- English
- Resource Type
- Journal article
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- Citation topics
- 1 Clinical & Life Sciences
- 1.255 Musculoskeletal Disorders
- 1.255.1081 Microgravity Muscle Adaptation
- Web Of Science research areas
- Clinical Neurology
- ESI research areas
- Neuroscience & Behavior