Journal article
Patterns of muscle involvement in inclusion body myositis: Clinical and magnetic resonance imaging study
Muscle & Nerve, Vol.24(11), pp.1526-1534
2001
Abstract
The differential patterns of muscle involvement in the upper and lower limbs in sporadic inclusion body myositis (sIBM) were examined in 18 patients using both quantitative and manual muscle testing as well as magnetic resonance imaging (MRI) in 9 patients. Weakness of the quadriceps femoris and the forearm flexors was present in most patients, but there was considerable variability in the patterns and severity of muscle involvement. MRI disclosed preferential patterns of muscle involvement within functional groups such as the quadriceps femoris, in which there was severe involvement of the vasti with relative sparing of the rectus femoris, and the triceps surae, in which selective involvement of the medial gastrocnemius was common. Involvement of flexor digitorum profundus on MRI was found in only one third of patients. The results emphasize the variability in the clinical phenotype and differential susceptibility of muscles to the disease process in sIBM.
Details
- Title
- Patterns of muscle involvement in inclusion body myositis: Clinical and magnetic resonance imaging study
- Authors/Creators
- B.A. Phillips (Author/Creator)L.A. Cala (Author/Creator)G.W. Thickbroom (Author/Creator)A. Melsom (Author/Creator)P.J. Zilko (Author/Creator)F.L. Mastaglia (Author/Creator)
- Publication Details
- Muscle & Nerve, Vol.24(11), pp.1526-1534
- Publisher
- John Wiley and Sons Inc.
- Identifiers
- 991005543900507891
- Copyright
- © 2001 John Wiley & Sons, Inc.
- Murdoch Affiliation
- Murdoch University
- Language
- English
- Resource Type
- Journal article
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- Citation topics
- 1 Clinical & Life Sciences
- 1.106 Rheumatology
- 1.106.1684 Dermatomyositis
- Web Of Science research areas
- Clinical Neurology
- Neurosciences
- ESI research areas
- Neuroscience & Behavior