Pesticides in human milk of Western Australian women and their influence on infant growth outcomes: A cross-sectional study

J. Du; Z. Gridneva; M.C.L. Gay; R.D. Trengove; P.E. Hartmann; D.T. Geddes

doi:10.1016/j.chemosphere.2016.10.005

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Pesticides in human milk of Western Australian women and their influence on infant growth outcomes: A cross-sectional study

Journal article

Peer reviewed

Pesticides in human milk of Western Australian women and their influence on infant growth outcomes: A cross-sectional study

J. Du, Z. Gridneva, M.C.L. Gay, R.D. Trengove, P.E. Hartmann and D.T. Geddes

Chemosphere, Vol.167, pp.247-254

2017

DOI: https://doi.org/10.1016/j.chemosphere.2016.10.005

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Abstract

Persistent organic pollutants in human milk (HM) at high levels are considered to be detrimental to the breastfed infant. To determine the pesticide concentration in HM, a pilot cross-sectional study of 40 Western Australian (WA) women was carried out. Gas chromatography-tandem mass spectrometry (GC-MS/MS) with a validated QuEChERS was used for the analysis of 88 pesticides in HM. p,p′-dichlorodiphenyldichloroethylene (p,p′-DDE) with a mean concentration of 62.8 ± 54.5 ng/g fat was found, whereas other organochlorines, organophosphates, carbamates and pyrethroids were not detected in HM. Overall, no association was observed between HM p,p′-DDE concentrations and maternal age, parity, body mass index and percentage fat mass. Furthermore, for the first time no significant association was found between p,p′-DDE concentrations in HM and infant growth outcomes such as weight, length, head circumference and percentage fat mass. The calculated daily intake was significantly different to the estimated daily intake of total DDTs and was well below the guideline proposed by WHO. The DDTs levels in WA have also significantly decreased by 42 - fold since the 1970s and are currently the lowest in Australia.

Details

Title: Pesticides in human milk of Western Australian women and their influence on infant growth outcomes: A cross-sectional study
Authors/Creators: J. Du (Author/Creator) - The University of Western Australia
Z. Gridneva (Author/Creator) - The University of Western Australia
M.C.L. Gay (Author/Creator)
R.D. Trengove (Author/Creator) - Murdoch University
P.E. Hartmann (Author/Creator) - The University of Western Australia
D.T. Geddes (Author/Creator) - The University of Western Australia
Publication Details: Chemosphere, Vol.167, pp.247-254
Publisher: Elsevier
Identifiers: 991005544005407891
Copyright: © 2016 Elsevier Ltd
Murdoch Affiliation: Separation Science and Metabolomics Laboratory
Language: English
Resource Type: Journal article

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Collaboration types: Domestic collaboration
Citation topics: 3 Agriculture, Environment & Ecology; 3.60 Herbicides, Pesticides & Ground Poisoning; 3.60.221 Persistent Organic Pollutants
Web Of Science research areas: Environmental Sciences
ESI research areas: Environment/Ecology