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Phylogenetic relationships and protein modelling revealed two distinct subfamilies of group II HKT genes between crop and model grasses
Journal article   Peer reviewed

Phylogenetic relationships and protein modelling revealed two distinct subfamilies of group II HKT genes between crop and model grasses

H.A.K. Ariyarathna, M.G. Francki and F. Belzile
Genome, Vol.59(7), pp.509-517
2016
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Abstract

Molecular evolution of large protein families in closely related species can provide useful insights on structural functional relationships. Phylogenetic analysis of the grass-specific group II HKT genes identified two distinct subfamilies, I and II. Subfamily II was represented in all species, whereas subfamily I was identified only in the small grain cereals and possibly originated from an ancestral gene duplication post divergence from the coarse grain cereal lineage. The core protein structures were highly analogous despite there being no more than 58% amino acid identity between members of the two subfamilies. Distinctly variable regions in known functional domains, however, indicated functional divergence of the two subfamilies. The subsets of codons residing external to known functional domains predicted signatures of positive Darwinian selection potentially identifying new domains of functional divergence and providing new insights on the structural function and relationships between protein members of the two subfamilies.

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Collaboration types
Domestic collaboration
Citation topics
3 Agriculture, Environment & Ecology
3.4 Crop Science
3.4.49 Plant Stress Responses
Web Of Science research areas
Biotechnology & Applied Microbiology
Genetics & Heredity
ESI research areas
Molecular Biology & Genetics
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