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Published (Version of Record)CC BY-NC V4.0, Open Access
Journal article
Physical activity patterns and clusters in 1001 patients with COPD
Chronic respiratory disease, Vol.14(3), pp.256-269
2017
PMCID: PMC5720232
PMID: 28774199
Abstract
We described physical activity measures and hourly patterns in patients with chronic obstructive pulmonary disease (COPD) after stratification for generic and COPD-specific characteristics and, based on multiple physical activity measures, we identified clusters of patients. In total, 1001 patients with COPD (65% men; age, 67 years; forced expiratory volume in the first second [FEV1], 49% predicted) were studied cross-sectionally. Demographics, anthropometrics, lung function and clinical data were assessed. Daily physical activity measures and hourly patterns were analysed based on data from a multisensor armband. Principal component analysis (PCA) and cluster analysis were applied to physical activity measures to identify clusters. Age, body mass index (BMI), dyspnoea grade and ADO index (including age, dyspnoea and airflow obstruction) were associated with physical activity measures and hourly patterns. Five clusters were identified based on three PCA components, which accounted for 60% of variance of the data. Importantly, couch potatoes (i.e. the most inactive cluster) were characterised by higher BMI, lower FEV1, worse dyspnoea and higher ADO index compared to other clusters (p < 0.05 for all). Daily physical activity measures and hourly patterns are heterogeneous in COPD. Clusters of patients were identified solely based on physical activity data. These findings may be useful to develop interventions aiming to promote physical activity in COPD.
Details
- Title
- Physical activity patterns and clusters in 1001 patients with COPD
- Authors/Creators
- Rafael Mesquita - CiroGabriele Spina - Eindhoven University of TechnologyFabio Pitta - Universidade Estadual de LondrinaDavid Donaire-Gonzalez - Center for Research in Environmental EpidemiologyBrenda M. Deering - Beaumont HospitalMehul S. Patel - Royal Brompton & Harefield NHS Fdn Trust, NIHR Resp Biomed Res Unit, London, EnglandKaty E. Mitchell - NIHR Leicester Biomedical Research CentreJennifer Alison - The University of SydneyArnoldus J. R. van Gestel - University Hospital of ZurichStefanie Zogg - University of BaselPhilippe Gagnon - Institut universitaire de cardiologie et de pneumologie de QuébecBeatriz Abascal-Bolado - Fundación Marques de ValdecillaBarbara Vagaggini - University of PisaJudith Garcia-Aymerich - Center for Research in Environmental EpidemiologySue C. Jenkins - Curtin UniversityElisabeth A. P. M. Romme - Catharina ZiekenhuisSamantha S. C. Kon - Royal Brompton & Harefield NHS Foundation TrustPaul S. Albert - Aintree University HospitalBenjamin Waschki - German Ctr Lung Res, Airway Res Ctr North, Pulm Res Inst, LungClin Grosshansdorf, Grosshansdorf, GermanyDinesh Shrikrishna - Royal Brompton & Harefield NHS Foundation TrustSally J. Singh - NIHR Leicester Biomedical Research CentreNicholas S. Hopkinson - Royal Brompton & Harefield NHS Foundation TrustDavid Miedinger - University of BaselRoberto P. Benzo - Mayo ClinicFrancois Maltais - Institut universitaire de cardiologie et de pneumologie de QuébecPierluigi Paggiaro - University of PisaZoe J. McKeough - The University of SydneyMichael I. Polkey - Royal Brompton & Harefield NHS Foundation TrustKylie Hill - Curtin UniversityWilliam D-C Man - Royal Brompton & Harefield NHS Foundation TrustChristian F. Clarenbach - University Hospital of ZurichNidia A. Hernandes - Universidade Estadual de LondrinaDaniela Savi - Sapienza University of RomeSally Wootton - The University of SydneyKarina C. Furlanetto - Universidade Estadual de LondrinaLi W. Cindy Ng - Curtin UniversityAnouk W. Vaes - CiroChristine Jenkins - Woolcock Institute of Medical ResearchPeter R. Eastwood - Sir Charles Gairdner HospitalDiana Jarreta - AstraZeneca (Spain)Anne Kirsten - German Ctr Lung Res, Airway Res Ctr North, Pulm Res Inst, LungClin Grosshansdorf, Grosshansdorf, GermanyDina Brooks - West Park Healthcare CentreDavid R. Hillman - Sir Charles Gairdner HospitalThais Sant'Anna - Universidade Estadual de LondrinaKenneth Meijer - Maastricht UniversitySelina Durr - University of BaselErica P. A. Rutten - CiroMalcolm Kohler - University Hospital of ZurichVanessa S. Probst - Universidade Estadual de LondrinaRuth Tal-Singer - GlaxoSmithKline (United States)Esther Garcia Gil - AstraZeneca, Barcelona, SpainAlbertus C. den Brinker - Philips Res, Smart Profess Spaces Grp, Eindhoven, NetherlandsJorg D. Leuppi - University of BaselPeter M. A. Calverley - Aintree University HospitalFrank W. J. M. Smeenk - Catharina ZiekenhuisRichard W. Costello - Beaumont HospitalMarco Gramm - German Ctr Lung Res, Airway Res Ctr North, Pulm Res Inst, LungClin Grosshansdorf, Grosshansdorf, GermanyRoger Goldstein - West Park Healthcare CentreMiriam T. J. Groenen - CiroHelgo Magnussen - German Ctr Lung Res, Airway Res Ctr North, Pulm Res Inst, LungClin Grosshansdorf, Grosshansdorf, GermanyEmiel F. M. Wouters - CiroRichard L. ZuWallack - Saint Francis UniversityOliver Amft - Eindhoven University of TechnologyHenrik Watz - German Ctr Lung Res, Airway Res Ctr North, Pulm Res Inst, LungClin Grosshansdorf, Grosshansdorf, GermanyMartijn A. Spruit - Ciro
- Publication Details
- Chronic respiratory disease, Vol.14(3), pp.256-269
- Publisher
- Sage
- Number of pages
- 14
- Grant note
- G0701628; G1002113 / Medical Research Council; UK Research & Innovation (UKRI); Medical Research Council UK (MRC) Medical Research Council, UK; UK Research & Innovation (UKRI); Medical Research Council UK (MRC) 041110 / Fundacio La Marato de TV3 SEPAR 2002/137 / Spanish Society of Pneumology and Thoracic Surgery 246704/2012-8 / National Council of Scientific and Technological Development (CNPq), Brazil; Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPQ) Gottfried und Julia Bangerter-Rhyner-Stiftung AgentschapNL, Dutch Ministry of Economic affairs, the Netherlands 'Forschungsfonds der Universitat Basel', Switzerland RTIC C03/09 / Red RCESP PI052486; PI052302 / Fondo de Investigacion Sanitaria; Instituto de Salud Carlos III; Spanish Government AATRM 035/20/02 / Agencia d'Avaluacio de Tecnologia i Recerca Mediques, Catalonia Government Freiwillige Akademische Gesellschaft Basel; General Electric CNPq, Brazil; Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPQ) Novartis Farmaceutica 2005SGR00392 / DURSI Astra Zeneca; AstraZeneca G0701628 / Medical Research Council, UK; UK Research & Innovation (UKRI); Medical Research Council UK (MRC) Coordination for the Improvement of Higher Education Personnel (CAPES), Brazil; Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES) GSK; GlaxoSmithKline FIS PI020541 / Fondo de Investigacion Sanitaria, Ministry of Health; Instituto de Salud Carlos III National Institute for Health Research, UK; National Institutes of Health Research (NIHR) RTIC C03/11 / Red RESPIRA AstraZeneca Farmaceutica; AstraZeneca Catalan Foundation of Pneumology (FUCAP Beca Maria Rava) GlaxoSmithKline Stichting de Weijerhorst G1002113; G0701628 / MRC; UK Research & Innovation (UKRI); Medical Research Council UK (MRC) DHCS/07/07/009; CTF-01-12-04 / National Institute for Health Research; National Institutes of Health Research (NIHR) 1042341 / NHMRC, Australia; National Health and Medical Research Council (NHMRC) of Australia NIHR Respiratory Biomedical Research Unit at the Royal Brompton and Harefield NHS Foundation Trust and Imperial College, UK 570814 / National Health and Medical Research Grant, Australia AgentschapNL, Dutch Ministry of Economic affairs, Netherlands
- Identifiers
- 991005592766107891
- Copyright
- © The Author(s) 2017
- Murdoch Affiliation
- Vice Chancellery
- Language
- English
- Resource Type
- Journal article
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- 1.65 Allergy
- 1.65.192 COPD
- Web Of Science research areas
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