Journal article
Possible role of common spices as a preventive and therapeutic agent for Alzheimer's disease
International Journal of Preventive Medicine, Vol.8(1), Article 5
2017
Abstract
For centuries, spices have been consumed as food additives or medicinal agents. However, there is increasing evidence indicating the plant-based foods in regular diet may lower the risk of neurodegenerative diseases including Alzheimer disease. Spices, as one of the most commonly used plant-based food additives may provide more than just flavors, but as agents that may prevent or even halt neurodegenerative processes associated with aging. In this article, we review the role and application of five commonly used dietary spices including saffron turmeric, pepper family, zingiber, and cinnamon. Besides suppressing inflammatory pathways, these spices may act as antioxidant and inhibit acetyl cholinesterase and amyloid β aggregation. We summarized how spice-derived nutraceuticals mediate such different effects and what their molecular targets might be. Finally, some directions for future research are briefly discussed.
Details
- Title
- Possible role of common spices as a preventive and therapeutic agent for Alzheimer's disease
- Authors/Creators
- R. Meamar (Author/Creator) - Isfahan University of Medical SciencesO. Mirmosayyeb (Author/Creator) - Isfahan University of Medical SciencesA. Tanhaei (Author/Creator) - Isfahan University of Medical SciencesH.R. Sohrabi (Author/Creator) - Islamic Azad University, IsfahanR.N. Martins (Author/Creator) - Islamic Azad University, IsfahanM. Tanhaei (Author/Creator) - Edith Cowan UniversityM.A. Najafi (Author/Creator) - Isfahan University of Medical SciencesA. Safaei (Author/Creator) - Isfahan University of Medical Sciences
- Publication Details
- International Journal of Preventive Medicine, Vol.8(1), Article 5
- Publisher
- Medknow Publications
- Identifiers
- 991005544985907891
- Copyright
- © 2017 International Journal of Preventive Medicine
- Murdoch Affiliation
- Murdoch University
- Language
- English
- Resource Type
- Journal article
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