Journal article
Potential functions of the human homeobox TGIFLX/Y genes in normal and abnormal development
European Journal of Clinical & Medical Oncology, Vol.4(1)
2012
Abstract
Homeobox genes encode transcription factors that play important roles in the developmental and normal cellular processes in all metazoans. TGIFLX/Y (TGIFLX and TGIFLY) are members of the homeobox superfamily of genes. Their expression is specifically detected in human adult testis but their functions remain to be investigated. Identification of relevant target genes should make a key contribution to a complete understanding of the mechanisms by which TGIFLX/Y functions in both normal and abnormal developmental processes. In this review, we provide an overview of recent studies on different aspects of TGIFLX/Y with a focus on the current state of research about their roles in tumorigenesis and azoospermia.
Details
- Title
- Potential functions of the human homeobox TGIFLX/Y genes in normal and abnormal development
- Authors/Creators
- L. Youssefian (Author/Creator)H. Vahidnezhad (Author/Creator)R. Raoofian (Author/Creator)W. Greene (Author/Creator)M. Heidari (Author/Creator)
- Publication Details
- European Journal of Clinical & Medical Oncology, Vol.4(1)
- Publisher
- San Lucas Medical
- Identifiers
- 991005546345707891
- Murdoch Affiliation
- School of Veterinary and Biomedical Sciences
- Language
- English
- Resource Type
- Journal article
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