Journal article
Potential role of curcumin for the treatment of major depressive disorder
CNS Drugs, Vol.36, pp.123-141
2022
Abstract
Curcumin is the major biologically active polyphenolic constituent in the turmeric plant (Curcuma longa) that has been shown to have antioxidant, anti-inflammatory, neuroprotective, anticancer, antimicrobial, and cardioprotective effects. Interest in curcumin as a treatment for mental health conditions has increased and there is an expanding body of preclinical and clinical research examining its antidepressant and anxiolytic effects. In this narrative review, human trials investigating the effects of curcumin for the treatment of depression or depressive symptoms are summarised. Using findings from in vitro, animal, and human trials, possible biological mechanisms associated with the antidepressant effects of curcumin are also explored. To increase the understanding of curcumin for the treatment of depression, directions for future research are proposed.
Details
- Title
- Potential role of curcumin for the treatment of major depressive disorder
- Authors/Creators
- A.L. Lopresti (Author/Creator) - Murdoch University
- Publication Details
- CNS Drugs, Vol.36, pp.123-141
- Publisher
- Springer International Publishing
- Identifiers
- 991005544497407891
- Copyright
- © 2022 The Authors.
- Murdoch Affiliation
- College of Science, Health, Engineering and Education
- Language
- English
- Resource Type
- Journal article
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Source: InCites
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- Citation topics
- 3 Agriculture, Environment & Ecology
- 3.16 Phytochemicals
- 3.16.1399 Curcumin
- Web Of Science research areas
- Clinical Neurology
- Pharmacology & Pharmacy
- Psychiatry
- ESI research areas
- Neuroscience & Behavior