Journal article
Primary localized cutaneous nodular amyloidosis successfully treated with cyclophosphamide
The Australasian Journal of Dermatology, Vol.54(1), pp.e12-e15
02/2013
Abstract
Primary localized cutaneous nodular amyloidosis (PLCNA) is a rare subtype of localized cutaneous amyloidosis and can be associated with various connective tissue disorders. It can be difficult to treat and past therapies include surgical excision, dermabrasion, electrodessication and curettage, cryotherapy and laser therapy. We present a case of a middle-aged woman with PLCNA associated with CREST (calcinosis, Raynaud phenomenon, oesophageal motility disorders, sclerodactyly and telangiectasia) syndrome and Sjögren's syndrome responding to cyclophosphamide with no new amyloid deposits and resolution of skin ulceration after many years of resistance to drug therapy. It is important to monitor these patients for progression into systemic amyloidosis.
Details
- Title
- Primary localized cutaneous nodular amyloidosis successfully treated with cyclophosphamide
- Authors/Creators
- P.L. Tong (Author/Creator)W.A. Walker (Author/Creator)R.J. Glancy (Author/Creator)J.P. Cooney (Author/Creator)K. Gebauer (Author/Creator)
- Publication Details
- The Australasian Journal of Dermatology, Vol.54(1), pp.e12-e15
- Publisher
- WILEY-BLACKWELL
- Number of pages
- 4
- Identifiers
- 991005541867007891
- Murdoch Affiliation
- School of Nursing and Midwifery
- Language
- English
- Resource Type
- Journal article
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- Collaboration types
- Domestic collaboration
- International collaboration
- Citation topics
- 1 Clinical & Life Sciences
- 1.281 Auto-inflammatory Diseases
- 1.281.1236 Amyloidosis
- Web Of Science research areas
- Dermatology
- ESI research areas
- Clinical Medicine