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Production of siderophore by coagulase-negative staphylococci and its relation to virulence
Journal article   Peer reviewed

Production of siderophore by coagulase-negative staphylococci and its relation to virulence

J.A. Lindsay, T.V. Riley and B.J. Mee
European Journal of Clinical Microbiology & Infectious Diseases, Vol.13(12), pp.1063-1066
1994
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Abstract

The ability to produce siderophore is considered to be a virulence factor for many pathogenic bacteria. To determine if siderophore production by coagulase-negative staphylococci (CNS) was related to virulence, 40 clinical isolates of CNS cultured from peritoneal dialysis fluid were compared with 38 commensal skin isolates. Siderophore activity was detected using the chrome azurol S liquid assay. Using precursor studies, Staphylococcus epidermidis isolates were shown to be more likely to produce the siderophore staphyloferrin A. Production of staphyloferrin B amongst non-Staphylococcus epidermidis species was associated with clinical isolates rather than commensal isolates, and therefore may play a role in pathogenicity

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Collaboration types
Domestic collaboration
Citation topics
1 Clinical & Life Sciences
1.42 Bacteriology
1.42.839 Outer Membrane
Web Of Science research areas
Infectious Diseases
Microbiology
ESI research areas
Microbiology
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