Prospects for developing allergen‐depleted food crops

Vadthya Lokya; Sejal Parmar; Arun K. Pandey; Hari K. Sudini; Dongxin Huai; Peggy Ozias-Akins; Christine H. Foyer; Chogozie Victor Nwosu; Barbara Karpinska; Alison Baker; Pei Xu; Boshou Liao; Reyazul Rouf Mir; Xiaoping Chen; Baozhu Guo; Henry T. Nguyen; Rakesh Kumar; Sandeep K. Bera; Prashant Singam; Anirudh Kumar; Rajeev K. Varshney; Manish K. Pandey

doi:10.1002/tpg2.20375

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Prospects for developing allergen‐depleted food crops

Journal article

Open access

Peer reviewed

Prospects for developing allergen‐depleted food crops

Vadthya Lokya, Sejal Parmar, Arun K. Pandey, Hari K. Sudini, Dongxin Huai, Peggy Ozias-Akins, Christine H. Foyer, Chogozie Victor Nwosu, Barbara Karpinska, Alison Baker, …

The plant genome, Vol.16(4), e20375

2023

DOI: https://doi.org/10.1002/tpg2.20375

PMID: 37641460

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Abstract

Allergens

Animals

Arachis

Crops, Agricultural

Food Hypersensitivity

Glycine max

Nuts

In addition to the challenge of meeting global demand for food production, there are increasing concerns about food safety and the need to protect consumer health from the negative effects of foodborne allergies. Certain bio‐molecules (usually proteins) present in food can act as allergens that trigger unusual immunological reactions, with potentially life‐threatening consequences. The relentless working lifestyles of the modern era often incorporate poor eating habits that include readymade prepackaged and processed foods, which contain additives such as peanuts, tree nuts, wheat, and soy‐based products, rather than traditional home cooking. Of the predominant allergenic foods (soybean, wheat, fish, peanut, shellfish, tree nuts, eggs, and milk), peanuts ( Arachis hypogaea ) are the best characterized source of allergens, followed by tree nuts ( Juglans regia , Prunus amygdalus , Corylus avellana , Carya illinoinensis , Anacardium occidentale , Pistacia vera , Bertholletia excels ), wheat ( Triticum aestivum ), soybeans ( Glycine max ), and kidney beans ( Phaseolus vulgaris ). The prevalence of food allergies has risen significantly in recent years including chance of accidental exposure to such foods. In contrast, the standards of detection, diagnosis, and cure have not kept pace and unfortunately are often suboptimal. In this review, we mainly focus on the prevalence of allergies associated with peanut, tree nuts, wheat, soybean, and kidney bean, highlighting their physiological properties and functions as well as considering research directions for tailoring allergen gene expression. In particular, we discuss how recent advances in molecular breeding, genetic engineering, and genome editing can be used to develop potential low allergen food crops that protect consumer health.

Details

Title: Prospects for developing allergen‐depleted food crops
Authors/Creators: Vadthya Lokya - International Crops Research Institute for the Semi‐Arid Tropics (ICRISAT) Hyderabad India
Sejal Parmar - International Crops Research Institute for the Semi-Arid Tropics
Arun K. Pandey - China Jiliang University
Hari K. Sudini - International Crops Research Institute for the Semi‐Arid Tropics (ICRISAT) Hyderabad India
Dongxin Huai - Ministry of Agriculture and Rural Affairs
Peggy Ozias-Akins - Horticulture Department The University of Georgia Tifton Campus Tifton GA USA
Christine H. Foyer - University of Birmingham
Chogozie Victor Nwosu - MARS‐Wrigley Chicago IL USA
Barbara Karpinska - University of Birmingham
Alison Baker - University of Leeds
Pei Xu - China Jiliang University
Boshou Liao - Ministry of Agriculture and Rural Affairs
Reyazul Rouf Mir - Faculty (United Kingdom)
Xiaoping Chen - Guangdong Academy of Agricultural Sciences
Baozhu Guo - USDA‐ARS, Crop Genetics and Breeding Research Unit Tifton GA USA
Henry T. Nguyen - University of Missouri
Rakesh Kumar - Central University of Karnataka
Sandeep K. Bera - ICAR‐Directorate of Groundnut Research Junagadh India
Prashant Singam - Osmania University
Anirudh Kumar - Central Tribal University of Andhra Pradesh Vizianagaram Andhra Pradesh India
Rajeev K. Varshney - Murdoch University, Food Futures Institute
Manish K. Pandey - International Crops Research Institute for the Semi-Arid Tropics
Publication Details: The plant genome, Vol.16(4), e20375
Publisher: Wiley Periodicals LLC on behalf of Crop Science Society of America.
Grant note: OPP1114827 / Bill and Melinda Gates Foundation
Identifiers: 991005601869607891
Murdoch Affiliation: Centre for Crop and Food Innovation; State Agricultural Biotechnology Centre
Language: English
Resource Type: Journal article

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Collaboration types: Industry collaboration; Domestic collaboration; International collaboration
Citation topics: 1 Clinical & Life Sciences; 1.65 Allergy; 1.65.264 Allergy Mechanisms
Web Of Science research areas: Genetics & Heredity; Plant Sciences
ESI research areas: Plant & Animal Science