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Protein binding of iron in blood plasma of the ascidian Herdmania momus
Journal article   Peer reviewed

Protein binding of iron in blood plasma of the ascidian Herdmania momus

J. Webb and P. Chrystal
Marine Biology, Vol.63(2), pp.107-112
1981
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Abstract

Blood of the ascidian Herdmania momus var. grandii (Kott, 1952) has typically a low cell haematocrit volume, <1% with a cell density of 12 000 to 15 000 cells mm-3. Non-dialysable solids in the plasma are 105±10 mg%. Iron-binding in the plasma has been investigated by fractionation of 59Fe-labelled plasma, using gel chromatography and electrophoretic procedures. Three fractions, identified as I, II and III in the order of their elution from a G-150 column, bind 59Fe in the ratio 60:15:15. The dominant fraction, I, was shown by electrophoresis on polyacrylamide gels to consist of two components in the ratio of ca. 80:20 and with similar electrophoretic mobilities. Dissociation of Fraction I by mercaptoethanol and sodium dodecyl sulfate gave on electrophoresis three components of molecular weights 17 000; 32 000 and 66 000. Fraction 1 contained 10% carbohydrate by weight as determined by the ℓ-cysteine/sulphuric acid assay. These data are compared with other iron-binding systems such as transferrin and the siderophores. Phylogenetic aspects of the study are also discussed.

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Citation topics
2 Chemistry
2.22 Inorganic & Nuclear Chemistry
2.22.1857 Vanadium Biochemistry
Web Of Science research areas
Marine & Freshwater Biology
ESI research areas
Plant & Animal Science
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