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Purification and characterization of diamine oxidase from clover leaves
Journal article   Peer reviewed

Purification and characterization of diamine oxidase from clover leaves

E. Delhaize and J. Webb
Phytochemistry, Vol.26(3), pp.641-643
1987
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Abstract

Diamine oxidase (DAO, EC 1.4.3.6) was purified 135-fold from leaves of subterranean clover (Trifolium subterraneum L. cv Seaton Park) and three isoenzymes were identified. The native enzyme has an M of ca 150 000 and comprises two subunits both having an M, of 80 000. Clover DAO has a broad specificity range and is inhibited by copper ligands and reagents reactive towards carbonyl groups. Copper is essential for enzyme activity with the apoenzyme being reactivated specifically by copper. The enzyme has a broad pH optimum from pH 7-8 and an activation energy of 47 kJ/mol with 1,4-diaminobutane as substrate.

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Citation topics
1 Clinical & Life Sciences
1.320 Molecular & Cell Biology - Polyamines & Paraquat
1.320.1324 Polyamines
Web Of Science research areas
Biochemistry & Molecular Biology
Plant Sciences
ESI research areas
Plant & Animal Science
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