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Reaction of o-hydroxyphenyl alkyl ketones with phosphorus trichloride. Formation of 1,3,2-dioxaphosphorinans viaα-proton abstraction
Journal article   Peer reviewed

Reaction of o-hydroxyphenyl alkyl ketones with phosphorus trichloride. Formation of 1,3,2-dioxaphosphorinans viaα-proton abstraction

G.M.L. Cragg, B. Davidowitz, R.G.F. Giles and R.J. Haines
Journal of the Chemical Society, Chemical Communications, (16), pp.569-570
1977
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Abstract

Treatment of PCl3 with o-HOC6H4COCH2R (R = H or Et) and NEt3 affords 2-chloro-1,3,2-dioxaphosphorinans, which can be readily converted into the corresponding 2-alkoxy derivatives; evidence is presented for the formation of analogous derivatives on similar reaction of acetylacetone and PCl3.

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