Journal article
Recovery of viral agents from the central nervous system of cats
Veterinary Microbiology, Vol.9(4), pp.355-66
08/1984
Abstract
Isolation of viruses from the central nervous system (CNS) of cats was attempted using an explant culture technique and subsequent co-cultivation with Crandell feline kidney (CRFK) or Vero cells. Feline syncytia-forming virus was isolated from the CNS of 11 of 16 cats where the initial co-cultivation was with CRFK cells. Feline panleucopaenia virus was isolated from the CNS of 2 adult cats. Co-cultured cells from the CNS of 3 cats contained eosinophilic cytoplasmic and intranuclear inclusions. The cytoplasmic inclusions consisted of tubular structures, 16-18 nm in diameter and up to 500 nm in length, which were similar in morphology to paramyxovirus nucleocapsids. The 3 co-cultured cells with cytoplasmic and intranuclear inclusions showed haemadsorption of guinea pig erythrocytes. The possible identity of these structures, and their association with a previously described primary focal demyelinating lesion in the CNS of cats, is discussed.
Details
- Title
- Recovery of viral agents from the central nervous system of cats
- Authors/Creators
- G.E. Wilcox (Author/Creator)R.L. Flower (Author/Creator)R.D. Cook (Author/Creator)
- Publication Details
- Veterinary Microbiology, Vol.9(4), pp.355-66
- Publisher
- Elsevier BV
- Identifiers
- 991005544235107891
- Murdoch Affiliation
- School of Veterinary Studies
- Language
- English
- Resource Type
- Journal article
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