Journal article
Reduced functional activation after fatiguing exercise is not confined to primary motor areas
Experimental Brain Research, Vol.175(4), pp.575-583
2006
Abstract
We have previously shown that following a period of unimanual fatiguing exercise, there is a reduction in primary sensorimotor cortex (SM1) activation with movement of either the fatigued or the non-fatigued hand by Benwell et al. (Exp Brain Res 167:160–164, 2005). In the present study we have investigated whether this reduction is confined to motor areas or is more widespread. Functional imaging was performed before and after a 10-minute fatiguing exercise of the left hand (30% of maximum handgrip strength) in seven normal subjects (4 M, mean age 25 years). The activating task was a handgrip against a low resistance (1 kg) in response to a visual cue (chequerboard reversal every 2 ± 0.5 s). We compared activation in SM1, supplementary motor area (SMA), cerebellum (CB) and primary visual cortex (V1) before and after the fatiguing exercise. After exercise, contralateral SM1 activation was reduced by 33% (P < 0.05) compared to baseline for the fatigued hand and by 49% for the non-fatigued hand (P < 0.05). A similar pattern was seen for the bilateral SMA and ipsilateral CB following exercise (45 vs. 50% for SMA; 30 vs. 35% for CB; fatigued versus non-fatigued). Activation was also reduced in V1 but to a lesser extent than in motor areas (19 vs. 24%; fatigued versus non-fatigued). These results show that although the reduced functional activation during the recovery period after fatiguing exercise is more marked in motor areas, it also extends to non-motor areas such as the visual cortex, suggesting that there are more widespread changes in cerebral haemodynamic responses after fatigue.
Details
- Title
- Reduced functional activation after fatiguing exercise is not confined to primary motor areas
- Authors/Creators
- N.M. Benwell (Author/Creator) - Queen Elizabeth II Medical CentreF.L. Mastaglia (Author/Creator) - Queen Elizabeth II Medical CentreG.W. Thickbroom (Author/Creator) - Queen Elizabeth II Medical Centre
- Publication Details
- Experimental Brain Research, Vol.175(4), pp.575-583
- Publisher
- Springer-Verlag Berlin Heidelberg
- Identifiers
- 991005544465907891
- Murdoch Affiliation
- Murdoch University
- Language
- English
- Resource Type
- Journal article
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- 1 Clinical & Life Sciences
- 1.82 Gait & Posture
- 1.82.811 Transcranial Magnetic Stimulation
- Web Of Science research areas
- Neurosciences
- ESI research areas
- Neuroscience & Behavior