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Regioselectivity in the reactions of methoxydehydrobenzenes with furans. Part 2. 2-Methoxyfuran and methoxydehydrobenzenes
Journal article   Peer reviewed

Regioselectivity in the reactions of methoxydehydrobenzenes with furans. Part 2. 2-Methoxyfuran and methoxydehydrobenzenes

R.G.F. Giles, A.B. Hughes and M.V. Sargent
Journal of the Chemical Society, Perkin Transactions 1, (6), pp.1581-1587
1991
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Abstract

Acid-induced ring opening of adducts of furan and methoxydehydrobenzenes gives the naphthalenols derived from the more stable carbocation. The cycloadditions of methoxydehydrobenzenes containing a 3-methoxy group and 2-methoxyfuran are highly regiospecific. The adducts, being strained acetals, undergo ring opening to provide a convenient synthesis of naphthalenols.

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