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Research directions in genetic predispositions to Stevens-Johnson Syndrome / Toxic Epidermal Necrolysis
Journal article   Peer reviewed

Research directions in genetic predispositions to Stevens-Johnson Syndrome / Toxic Epidermal Necrolysis

T.A. Manolio, C.M. Hutter, M. Avigan, R. Cibotti, R.L. Davis, J.C. Denny, L.L. Grenade, L.M. Wheatley, M.N. Carrington, W. Chantratita, …
Clinical Pharmacology & Therapeutics, Vol.103(3), pp.390-394
2017
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Abstract

Stevens–Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) is one of the most devastating of adverse drug reactions (ADRs) and was, until recently, essentially unpredictable. With the discovery of several risk alleles for drug-induced SJS/TEN and the demonstration of effectiveness of screening in reducing incidence, the stage is set for implementation of preventive strategies in populations at risk. Yet much remains to be learned about this potentially fatal complication of commonly used drugs.

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Collaboration types
Domestic collaboration
International collaboration
Citation topics
1 Clinical & Life Sciences
1.265 Dermatology - Skin Allergies
1.265.1140 Drug Hypersensitivity
Web Of Science research areas
Pharmacology & Pharmacy
ESI research areas
Pharmacology & Toxicology
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