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Responses of erectile tissue from impotent men to pharmacological agents
Journal article   Peer reviewed

Responses of erectile tissue from impotent men to pharmacological agents

K.E. Creed, C.J. Carati, G.M. Adamson and S.M. Callahan
British Journal of Urology, Vol.63(4), pp.428-431
1989
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Abstract

Erectile tissue was removed from the corpora cavernosa of 25 impotent men undergoing surgery for insertion of penile prostheses. Strips, set up in an organ bath, were contracted by the alpha-adrenergic agonist phenylephrine. There was no significant difference between tissue taken from men with diabetes, alcoholism, Peyronie's disease or men with no obvious condition causing the impotence. The sensitivity of tissues from hypertensive patients was significantly reduced but this was probably due to drugs being taken for hypertension. Precontracted tissues could be relaxed by acetylcholine or isoprenaline. The responses, however, were inconsistent, so that no difference between the different groups of patients was apparent.

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Source: InCites

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Collaboration types
Domestic collaboration
Citation topics
1 Clinical & Life Sciences
1.142 Urology
1.142.484 Sexual Dysfunction
Web Of Science research areas
Urology & Nephrology
ESI research areas
Clinical Medicine
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