Journal article
SJS/TEN 2017: Building multidisciplinary networks to drive science and translation
The Journal of Allergy and Clinical Immunology: In Practice, Vol.6(1), pp.38-69
2018
Abstract
Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) is a life-threatening, immunologically mediated, and usually drug-induced disease with a high burden to individuals, their families, and society with an annual incidence of 1 to 5 per 1,000,000. To effect significant reduction in short- and long-term morbidity and mortality, and advance clinical care and research, coordination of multiple medical, surgical, behavioral, and basic scientific disciplines is required. On March 2, 2017, an investigator-driven meeting was held immediately before the American Academy of Dermatology Annual meeting for the central purpose of assembling, for the first time in the United States, clinicians and scientists from multiple disciplines involved in SJS/TEN clinical care and basic science research. As a product of this meeting, this article summarizes the current state of knowledge and expert opinion related to SJS/TEN covering a broad spectrum of topics including epidemiology and pharmacogenomic networks; clinical management and complications; special populations such as pediatrics, the elderly, and pregnant women; regulatory issues and the electronic health record; new agents that cause SJS/TEN; pharmacogenomics and immunopathogenesis; and the patient perspective. Goals include the maintenance of a durable and productive multidisciplinary network that will significantly further scientific progress and translation into prevention, early diagnosis, and management of SJS/TEN.
Details
- Title
- SJS/TEN 2017: Building multidisciplinary networks to drive science and translation
- Authors/Creators
- K.D. White (Author/Creator) - Vanderbilt University Medical CenterR. Abe (Author/Creator) - Niigata UniversityM. Ardern-Jones (Author/Creator) - University of SouthamptonT. Beachkofsky (Author/Creator) - Wilford Hall Ambulatory Surgical CenterC. Bouchard (Author/Creator) - Loyola University Medical CenterB. Carleton (Author/Creator) - BC Children's HospitalJ. Chodosh (Author/Creator) - Massachusetts Eye and Ear InfirmaryR. Cibotti (Author/Creator) - National Institute of Arthritis and Musculoskeletal and Skin DiseasesR. Davis (Author/Creator) - University of Tennessee at KnoxvilleJ.C. Denny (Author/Creator) - Vanderbilt University Medical CenterR.P. Dodiuk-Gad (Author/Creator) - Emek Medical CenterE.N. Ergen (Author/Creator) - University of Alabama at BirminghamJ.L. Goldman (Author/Creator) - Children's Mercy HospitalJ.H. Holmes (Author/Creator) - Atrium Health Wake Forest BaptistS-L Hung (Author/Creator)M.E. Lacouture (Author/Creator) - Memorial Sloan Kettering Cancer CenterR.J. Lehloenya (Author/Creator) - Groote Schuur HospitalS. Mallal (Author/Creator) - Murdoch UniversityT.A. Manolio (Author/Creator) - National Human Genome Research InstituteR.G. Micheletti (Author/Creator) - University of PennsylvaniaC.M. Mitchell (Author/Creator) - Massachusetts General HospitalM. Mockenhaupt (Author/Creator) - University Medical Center FreiburgD.A. Ostrov (Author/Creator) - University of FloridaR. Pavlos (Author/Creator) - Murdoch UniversityM. Pirmohamed (Author/Creator) - University of LiverpoolE. Pope (Author/Creator) - University of TorontoA. Redwood (Author/Creator) - Murdoch UniversityM. Rosenbach (Author/Creator) - University of PennsylvaniaM.D. Rosenblum (Author/Creator) - University of California, San FranciscoJ-C Roujeau (Author/Creator) - Université Paris-Est CréteilA.P. Saavedra (Author/Creator) - Massachusetts General HospitalH.N. Saeed (Author/Creator) - Massachusetts Eye and Ear InfirmaryJ.P. Struewing (Author/Creator) - National Human Genome Research InstituteH. Sueki (Author/Creator) - Showa UniversityC. Sukasem (Author/Creator) - Ramathibodi HospitalC. Sung (Author/Creator) - Duke-NUS Medical SchoolJ.A. Trubiano (Author/Creator) - The University of MelbourneJ. Weintraub (Author/Creator) - United States Food and Drug AdministrationL.M. Wheatley (Author/Creator) - National Institute of Allergy and Infectious DiseasesK.B. Williams (Author/Creator) - Vanderbilt University Medical CenterB. Worley (Author/Creator) - University of OttawaW-H Chung (Author/Creator) - Chang Gung Memorial HospitalN.H. Shear (Author/Creator) - Vanderbilt University Medical CenterE.J. Phillips (Author/Creator) - Murdoch University
- Publication Details
- The Journal of Allergy and Clinical Immunology: In Practice, Vol.6(1), pp.38-69
- Publisher
- Elsevier
- Identifiers
- 991005541623307891
- Copyright
- © 2017 American Academy of Allergy, Asthma & Immunology
- Murdoch Affiliation
- Institute for Immunology and Infectious Diseases
- Language
- English
- Resource Type
- Journal article
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- Collaboration types
- Domestic collaboration
- International collaboration
- Citation topics
- 1 Clinical & Life Sciences
- 1.265 Dermatology - Skin Allergies
- 1.265.1140 Drug Hypersensitivity
- Web Of Science research areas
- Allergy
- Immunology
- ESI research areas
- Clinical Medicine