Salmonella enterica isolates from Western Australian rangeland goats remain susceptible to critically important antimicrobials

K. Al-Habsi; D. Jordan; A. Harb; T. Laird; R. Yang; M. O’Dea; C. Jacobson; D.W. Miller; U. Ryan; S. Abraham

doi:10.1038/s41598-018-33220-5

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Salmonella enterica isolates from Western Australian rangeland goats remain susceptible to critically important antimicrobials

Journal article

Open access

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Salmonella enterica isolates from Western Australian rangeland goats remain susceptible to critically important antimicrobials

K. Al-Habsi, D. Jordan, A. Harb, T. Laird, R. Yang, M. O’Dea, C. Jacobson, D.W. Miller, U. Ryan and S. Abraham

Scientific Reports, Vol.8(1), Article number: 15326

2018

DOI: https://doi.org/10.1038/s41598-018-33220-5

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Abstract

This study investigated faecal carriage and antimicrobial resistance (AMR) of Salmonella enterica recovered from rangeland goats. Faecal samples (n = 400) were collected at slaughter from four consignments of goats (n = 100 samples per consignment), each from one of four localities in Western Australia. Carriage of Salmonella spp. was detected in 106 samples (26.5%; 95% CI 22.4–31.0%). The rate of faecal carriage for each consignment ranged between 23–30%. PCR assays targeting the STM2755 and STM4497 genes revealed 84.9% (90/106) of the isolates were of serovar Typhimurium. Salmonella Chester (11/106, 10.4%) and S. Saintpaul (5/106, 4.7%) were characterised at invA and ompF genes. Antimicrobial susceptibility testing demonstrated that 84.0% of isolates were susceptible to all tested (n = 13) antimicrobials. Resistance was identified to azithromycin (14.2%), tetracycline (10.4%), ampicillin (5.7%), amoxicillin–clavulanate and cefoxitin (3.8%), trimethoprim/sulfamethoxazole (1.9%), gentamicin and streptomycin (0.9%). No isolate was resistant to four or more antimicrobials, or to critically important antimicrobials such as fluoroquinolones and extended spectrum cephalosporins. This is the first study reporting AMR in Salmonella isolates from Australian rangeland goats. The rate of detection of AMR was very low, some resistance to low-importance drugs was present in the Salmonella population, despite the absence of active selection pressure.

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Title: Salmonella enterica isolates from Western Australian rangeland goats remain susceptible to critically important antimicrobials
Authors/Creators: K. Al-Habsi (Author/Creator) - Murdoch University
D. Jordan (Author/Creator) - New South Wales Department of Primary Industries
A. Harb (Author/Creator) - Murdoch University
T. Laird (Author/Creator) - Murdoch University
R. Yang (Author/Creator) - Murdoch University
M. O’Dea (Author/Creator) - Murdoch University
C. Jacobson (Author/Creator) - Murdoch University
D.W. Miller (Author/Creator) - Murdoch University
U. Ryan (Author/Creator) - Murdoch University
S. Abraham (Author/Creator) - Murdoch University
Publication Details: Scientific Reports, Vol.8(1), Article number: 15326
Publisher: Nature Research
Identifiers: 991005545307607891
Copyright: © The Author(s) 2018
Murdoch Affiliation: School of Veterinary and Life Sciences
Language: English
Resource Type: Journal article

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Collaboration types: Domestic collaboration
Citation topics: 1 Clinical & Life Sciences; 1.42 Bacteriology; 1.42.376 Salmonella and Campylobacter
Web Of Science research areas: Microbiology
ESI research areas: Plant & Animal Science