Journal article
Selection on mitochondrial variants occurs between and within individuals in an expanding invasion
Molecular Biology and Evolution, Vol.33(4), pp.995-1007
2016
Abstract
Mitochondria are critical for life, yet their underlying evolutionary biology is poorly understood. In particular, little is known about interaction between two levels of evolution: between individuals and within individuals (competition between cells, mitochondria or mitochondrial DNA molecules). Rapid evolution is suspected to occur frequently in mitochondrial DNA, whose maternal inheritance predisposes advantageous mutations to sweep rapidly though populations. Rapid evolution is also predicted in response to changed selection regimes after species invasion or removal of pathogens or competitors. Here, using empirical and simulated data from a model invasive bird species, we provide the first demonstration of rapid selection on the mitochondrial genome within individuals in the wild. Further, we show differences in mitochondrial DNA copy number associated with competing genetic variants, which may provide a mechanism for selection. We provide evidence for three rarely documented phenomena: selection associated with mitochondrial DNA abundance, selection on the mitochondrial control region, and contemporary selection during invasion.
Details
- Title
- Selection on mitochondrial variants occurs between and within individuals in an expanding invasion
- Authors/Creators
- L.A. Rollins (Author/Creator)A.P. Woolnough (Author/Creator)B.G. Fanson (Author/Creator)M.L. Cummins (Author/Creator)T.M. Crowley (Author/Creator)A.N. Wilton (Author/Creator)R. Sinclair (Author/Creator)A. Butler (Author/Creator)W.B. Sherwin (Author/Creator)
- Publication Details
- Molecular Biology and Evolution, Vol.33(4), pp.995-1007
- Publisher
- Oxford University Press
- Identifiers
- 991005543528707891
- Copyright
- © The Author(s) 2016.
- Murdoch Affiliation
- School of Veterinary and Life Sciences
- Language
- English
- Resource Type
- Journal article
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Source: InCites
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- Collaboration types
- Domestic collaboration
- Citation topics
- 1 Clinical & Life Sciences
- 1.197 Molecular & Cell Biology - Mitochondria
- 1.197.564 Mitochondrial Function
- Web Of Science research areas
- Biochemistry & Molecular Biology
- Evolutionary Biology
- Genetics & Heredity
- ESI research areas
- Molecular Biology & Genetics