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Serologic study of pig-associated viral zoonoses in Laos
Journal article   Open access   Peer reviewed

Serologic study of pig-associated viral zoonoses in Laos

J.V. Conlan, K. Vongxay, R.G. Jarman, R.V. Gibbons, R. A. Lunt, S. Fenwick, R.C.A. Thompson and S.D. Blacksell
American Journal of Tropical Medicine and Hygiene, Vol.86(6), pp.1077-1084
2012
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Abstract

We conducted a serologic survey of four high-priority pig-associated viral zoonoses, Japanese encephalitis virus (JEV), hepatitis E virus (HEV), Nipah virus (NiV), and swine influenza virus (SIV), in Laos. We collected blood from pigs at slaughter during May 2008-January 2009 in four northern provinces. Japanese encephalitis virus hemagglutination inhibition seroprevalence was 74.7% (95% confidence interval [CI] = 71.5-77.9%), JEV IgM seroprevalence was 2.3% (95% CI = 1.2-3.2%), and HEV seroprevalence was 21.1% (95% CI = 18.1-24.0%). Antibodies to SIV were detected in 1.8% (95% CI = 0.8-2.8%) of pigs by screening enzyme-linked immunosorbent assay, and only subtype H3N2 was detected by hemagglutination inhibition in two animals with an inconclusive enzyme-linked immunosorbent assay result. No NiV antibody-positive pigs were detected. Our evidence indicates that peak JEV and HEV transmission coincides with the start of the monsoonal wet season and poses the greatest risk for human infection.

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Collaboration types
Domestic collaboration
International collaboration
Citation topics
1 Clinical & Life Sciences
1.228 Virology - Tropical Diseases
1.228.200 Mosquito-borne Viruses
Web Of Science research areas
Public, Environmental & Occupational Health
Tropical Medicine
ESI research areas
Clinical Medicine
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