Journal article
Serum concentration of high density lipoproteins (HDLs) in leishmaniotic dogs
Research in Veterinary Science, Vol.98, pp.89-91
2015
Abstract
In order to assess whether the concentration of high density lipoproteins (HDLs) changes in leishmaniotic dogs before and after treatment, HDL cholesterol (HDL-Chol and HDL%), C reactive protein (CRP) and activity of the antioxidant enzyme paraoxonase (PON-1) were measured in sera from 10 controls and 10 leishmaniotic dogs. Seven of these latter were sampled also 3, 7, 14, 21 and 28 days after treatment with antimonials and allopurinol. HDL-chol, and PON-1 were low in leishmaniotic dogs at admission and increased after treatment. HDL-chol and HDL% correlated positively with PON-1 and negatively with CRP suggesting that HDLs decrease through an oxidative mechanism. Therefore, HDLs may be used to monitor the magnitude of oxidation associated with inflammation in leishmaniotic dogs.
Details
- Title
- Serum concentration of high density lipoproteins (HDLs) in leishmaniotic dogs
- Authors/Creators
- F. Ibba (Author/Creator) - University of MilanG. Rossi (Author/Creator) - University of MilanS. Meazzi (Author/Creator)A. Giordano (Author/Creator) - University of MilanS. Paltrinieri (Author/Creator) - University of Milan
- Publication Details
- Research in Veterinary Science, Vol.98, pp.89-91
- Publisher
- Elsevier Ltd.
- Identifiers
- 991005544253907891
- Copyright
- © 2014 Elsevier Ltd.
- Murdoch Affiliation
- Murdoch University
- Language
- English
- Resource Type
- Journal article
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- Citation topics
- 1 Clinical & Life Sciences
- 1.261 Parasitology - Trypanosoma & Leishmania
- 1.261.695 Leishmaniasis Dynamics
- Web Of Science research areas
- Veterinary Sciences
- ESI research areas
- Plant & Animal Science