Journal article
Serum concentrations of the derivatives of reactive oxygen metabolites (d-ROMs) in dogs with leishmaniosis
The Veterinary Journal, Vol.186(3), pp.393-395
2010
Abstract
Leishmania infantum interferes with the oxidative metabolism of phagocytes. In order to assess whether derivatives of reactive oxygen metabolites (d-ROMs) decrease due to infection or increase due to inflammation, d-ROMs were measured in serum collected from control dogs (Group 1; n=12), from dogs seropositive for Leishmania either symptomatic (Group 2; n=27) or not (Group 3; n=14), and from dogs with other diseases (Group 4; n=16). The concentrations of d-ROMs in the four groups, expressed in Carratelli Units (U CARR) were, respectively, 75.4 ± 39.5 (median, 81.6), 108.2 ± 96.3 (73.4), 73.5 ± 62.2 (62.0), 127.7 ± 97.3 (94.3). There were no significant differences between groups, but dogs with values higher than the reference interval were found, mostly in Groups 2 and 4 (which had serum C-reactive protein levels consistent with inflammation), whilst low values were occasionally found in Groups 2 and 3. Inflammation may mask decreases in d-ROMs induced by Leishmania infection.
Details
- Title
- Serum concentrations of the derivatives of reactive oxygen metabolites (d-ROMs) in dogs with leishmaniosis
- Authors/Creators
- S. Paltrinieri (Author/Creator)S. Ravicini (Author/Creator)G. Rossi (Author/Creator)X. Roura (Author/Creator)
- Publication Details
- The Veterinary Journal, Vol.186(3), pp.393-395
- Publisher
- Balliere Tindall
- Identifiers
- 991005545361007891
- Copyright
- © 2009 Elsevier Ltd.
- Murdoch Affiliation
- Murdoch University
- Language
- English
- Resource Type
- Journal article
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- Collaboration types
- Domestic collaboration
- International collaboration
- Citation topics
- 1 Clinical & Life Sciences
- 1.261 Parasitology - Trypanosoma & Leishmania
- 1.261.695 Leishmaniasis Dynamics
- Web Of Science research areas
- Veterinary Sciences
- ESI research areas
- Plant & Animal Science