Journal article
Serum paraoxonase-1 activity in neonatal calves: Age related variations and comparison between healthy and sick animals
The Veterinary Journal, Vol.197(2), pp.499-501
2013
Abstract
Early detection of inflammation in neonatal calves allows early intervention, which may reduce mortality. Paraoxonase-1 (PON1) is a negative acute phase protein in humans. The aims of this study were to investigate age-related variability in serum PON1 activity and its clinical usefulness in neonatal calves. In healthy calves (n= 9), PON1 activity increased with age from 2 to 21. days of age. There was no significant increase in PON1 activity in healthy calves from days 21 to 120 (n= 15), but PON1 activity was significantly higher in adult cattle (n= 45). In sick calves, serum PON1 was significantly lower in calves <7. days of age with diarrhoea (n= 8) and in calves >28- to 120-days-old with respiratory disease (n= 8) in comparison with age matched controls (n= 20 and n= 15, respectively). These results support the role of PON1 as a negative acute phase protein in cattle.
Details
- Title
- Serum paraoxonase-1 activity in neonatal calves: Age related variations and comparison between healthy and sick animals
- Authors/Creators
- A. Giordano (Author/Creator)M.C. Veronesi (Author/Creator)G. Rossi (Author/Creator)F. Pezzia (Author/Creator)M. Probo (Author/Creator)L. Giori (Author/Creator)S. Paltrinieri (Author/Creator)
- Publication Details
- The Veterinary Journal, Vol.197(2), pp.499-501
- Publisher
- Balliere Tindall
- Identifiers
- 991005545353807891
- Copyright
- © 2013 Elsevier Ltd.
- Murdoch Affiliation
- Murdoch University
- Language
- English
- Resource Type
- Journal article
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