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Solubility equilibria in the uric acid–sodium urate–water system
Journal article   Peer reviewed

Solubility equilibria in the uric acid–sodium urate–water system

Z. Wang and E. Königsberger
Thermochimica Acta, Vol.310(1-2), pp.237-242
1998
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Abstract

In a constant ionic medium, corresponding to a physiological environment (Ic=0.15moldm-3 NaCl), the solubilities of anhydrous uric acid, uric acid dihydrate and monosodium urate monohydrate have been measured as a function of p[H]=-log[H+](2-8) and temperature (25o, 32o, 37o and 42oC). The solubility equilibria in the uric acid-sodium urate-water system are discussed on the basis of the solubility constants (Ks) and the first dissociation constant (K1) of uric acid and the solubility product (Ks0) of monosodium urate. The quantities measured in this work are in good agreement with literature values, however, the present solubility data have a much higher precision.

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Citation topics
1 Clinical & Life Sciences
1.243 Kidney Diseases
1.243.519 Urolithiasis
Web Of Science research areas
Chemistry, Analytical
Chemistry, Physical
Thermodynamics
ESI research areas
Chemistry
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