Mathematics Physical Sciences Science & Technology Statistics & Probability
We calculate finite sample and asymptotic distributions for the largest censored and uncensored survival times, and some related statistics, from a sample of survival data generated according to an iid censoring model. These statistics are important for assessing whether there is sufficient follow-up in the sample to be confident of the presence of immune or cured individuals in the population. A key structural result obtained is that, conditional on the value of the largest uncensored survival time, and knowing the number of censored observations exceeding this time, the sample partitions into two independent subsamples, each subsample having the distribution of an iid sample of censored survival times, of reduced size, from truncated random variables. This result provides valuable insight into the construction of censored survival data, and facilitates the calculation of explicit finite sample formulae. We illustrate by calculating distributions of statistics useful for testing for sufficient follow-up in a sample, and apply extreme value methods to derive asymptotic distributions for some of those.
Details
Title
Splitting the sample at the largest uncensored observation
Authors/Creators
Ross Maller - Australian National University
Sidney Resnick - Cornell University
Soudabeh Shemehsavar - University of Tehran
Publication Details
Bernoulli : official journal of the Bernoulli Society for Mathematical Statistics and Probability, Vol.28(4), pp.2234-2259
Publisher
Bernoulli Society for Mathematical Statistics and Probability
Number of pages
26
Identifiers
991005618226407891
Murdoch Affiliation
College of Science, Technology, Engineering and Mathematics
Language
English
Resource Type
Journal article
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