Journal article
Successful treatment of macrophage activation syndrome complicating adult Still disease with anakinra
Internal Medicine Journal, Vol.42(12), pp.1358-1362
2012
Abstract
A previously healthy 20-year-old man presented with adult Still disease (ASD). He developed life-threatening macrophage activation syndrome (MAS), which was refractory to standard immunosuppression but responded dramatically to the IL-1 receptor antagonist anakinra. Subsequent immunological investigations included assessment of the perforin expression of natural killer (NK) cells and CD8+ T cells, which confirmed MAS.
Details
- Title
- Successful treatment of macrophage activation syndrome complicating adult Still disease with anakinra
- Authors/Creators
- N.K. Loh (Author/Creator) - Royal Perth HospitalM. Lucas (Author/Creator) - Murdoch UniversityS. Fernandez (Author/Creator) - The University of Western AustraliaD. Prentice (Author/Creator) - Royal Perth Hospital
- Publication Details
- Internal Medicine Journal, Vol.42(12), pp.1358-1362
- Publisher
- Blackwell Publishing
- Identifiers
- 991005542600707891
- Copyright
- © 2012 The Authors
- Murdoch Affiliation
- Centre for Clinical Immunology and Biomedical Statistics
- Language
- English
- Resource Type
- Journal article
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Source: InCites
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- Collaboration types
- Domestic collaboration
- Citation topics
- 1 Clinical & Life Sciences
- 1.106 Rheumatology
- 1.106.1646 Juvenile Arthritis & HLH
- Web Of Science research areas
- Rheumatology
- ESI research areas
- Clinical Medicine