Journal article
Supplementary motor area—primary motor cortex facilitation in younger but not older adults
Neurobiology of Aging, Vol.64, pp.85-91
2018
Abstract
Growing evidence implicates a decline in white matter integrity in the age-related decline in motor control. Functional neuroimaging studies show significant associations between functional connectivity in the cortical motor network, including the supplementary motor area (SMA), and motor performance. Dual-coil transcranial magnetic stimulation (TMS) studies show facilitatory connections between SMA and the primary motor cortex (M1) in younger adults. Here, we investigated whether SMA—M1 facilitation is affected by age, and whether the strength of SMA—M1 facilitation is associated with bilateral motor control. Dual-coil TMS was used to measure SMA—M1 connectivity in younger (N=20) and older adults (N=18), and bilateral motor control was measured with the assembly sub-test of the Purdue Pegboard and clinical measures of dynamic balance. SMA—M1 facilitation was seen in younger but not older adults, and a significant positive association was found between SMA—M1 facilitation and bimanual performance. These results show that SMA—M1 facilitation is reduced in older adults compared to younger adults, and provide evidence of the functional importance of SMA—M1 facilitation.
Details
- Title
- Supplementary motor area—primary motor cortex facilitation in younger but not older adults
- Authors/Creators
- P.E. Green (Author/Creator) - Murdoch UniversityM.C. Ridding (Author/Creator) - The University of AdelaideK.D. Hill (Author/Creator) - Curtin UniversityJ.G. Semmler (Author/Creator) - The University of AdelaideP.D. Drummond (Author/Creator) - Murdoch UniversityA.M. Vallence (Author/Creator) - Murdoch University
- Publication Details
- Neurobiology of Aging, Vol.64, pp.85-91
- Publisher
- Elsevier Inc
- Identifiers
- 991005543300007891
- Copyright
- © 2017 Published by Elsevier Inc.
- Murdoch Affiliation
- School of Psychology and Exercise Science
- Language
- English
- Resource Type
- Journal article
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- Collaboration types
- Domestic collaboration
- Citation topics
- 1 Clinical & Life Sciences
- 1.82 Gait & Posture
- 1.82.811 Transcranial Magnetic Stimulation
- Web Of Science research areas
- Geriatrics & Gerontology
- Neurosciences
- ESI research areas
- Neuroscience & Behavior