Survival, gene and metabolite responses of Litoria verreauxii alpina frogs to fungal disease chytridiomycosis

L.F. Grogan; J. Mulvenna; J.P.A. Gummer; B.C. Scheele; L. Berger; S.D. Cashins; M.S. McFadden; P. Harlow; D.A. Hunter; R.D. Trengove; L.F. Skerratt

doi:10.1038/sdata.2018.33

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Survival, gene and metabolite responses of Litoria verreauxii alpina frogs to fungal disease chytridiomycosis

Journal article

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Survival, gene and metabolite responses of Litoria verreauxii alpina frogs to fungal disease chytridiomycosis

L.F. Grogan, J. Mulvenna, J.P.A. Gummer, B.C. Scheele, L. Berger, S.D. Cashins, M.S. McFadden, P. Harlow, D.A. Hunter, R.D. Trengove, …

Scientific Data, Vol.5

2018

DOI: https://doi.org/10.1038/sdata.2018.33

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Abstract

The fungal skin disease chytridiomycosis has caused the devastating decline and extinction of hundreds of amphibian species globally, yet the potential for evolving resistance, and the underlying pathophysiological mechanisms remain poorly understood. We exposed 406 naïve, captive-raised alpine tree frogs (Litoria verreauxii alpina) from multiple populations (one evolutionarily naïve to chytridiomycosis) to the aetiological agent Batrachochytrium dendrobatidis in two concurrent and controlled infection experiments. We investigated (A) survival outcomes and clinical pathogen burdens between populations and clutches, and (B) individual host tissue responses to chytridiomycosis. Here we present multiple interrelated datasets associated with these exposure experiments, including animal signalment, survival and pathogen burden of 355 animals from Experiment A, and the following datasets related to 61 animals from Experiment B: animal signalment and pathogen burden; raw RNA-Seq reads from skin, liver and spleen tissues; de novo assembled transcriptomes for each tissue type; raw gene expression data; annotation data for each gene; and raw metabolite expression data from skin and liver tissues. These data provide an extensive baseline for future analyses.

Details

Title: Survival, gene and metabolite responses of Litoria verreauxii alpina frogs to fungal disease chytridiomycosis
Authors/Creators: L.F. Grogan (Author/Creator) - Griffith University
J. Mulvenna (Author/Creator) - QIMR Berghofer Medical Research Institute
J.P.A. Gummer (Author/Creator) - Murdoch University
B.C. Scheele (Author/Creator) - Australian National University
L. Berger (Author/Creator) - James Cook University
S.D. Cashins (Author/Creator) - James Cook University
M.S. McFadden (Author/Creator) - Taronga Conservation Society Australia
P. Harlow (Author/Creator) - Taronga Conservation Society Australia
D.A. Hunter (Author/Creator) - Office of Environment and Heritage
R.D. Trengove (Author/Creator) - Murdoch University
L.F. Skerratt (Author/Creator) - James Cook University
Publication Details: Scientific Data, Vol.5
Identifiers: 991005543681807891
Murdoch Affiliation: School of Veterinary and Life Sciences
Language: English
Resource Type: Journal article

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Collaboration types: Domestic collaboration
Citation topics: 3 Agriculture, Environment & Ecology; 3.35 Zoology & Animal Ecology; 3.35.790 Amphibian Ecology
Web Of Science research areas: Ecology
ESI research areas: Environment/Ecology