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Suspected paraneoplastic syndrome of inappropriate antidiuretic hormone secretion associated with a gastric adenocarcinoma in a dog
Journal article   Peer reviewed

Suspected paraneoplastic syndrome of inappropriate antidiuretic hormone secretion associated with a gastric adenocarcinoma in a dog

A. Thomas, J. Finlay and Claire R. Sharp
Australian Veterinary Journal, Early View
2024

Abstract

This report describes a suspected case of paraneoplastic syndrome of inappropriate antidiuretic hormone (SIADH) in a 5-year-old male entire Australian Kelpie associated with a gastric adenocarcinoma. The dog had a history of chronic vomiting and presented with hyponatraemia, hypokalaemia, hypochloraemia and increased urinary sodium. Computed tomography identified the presence of a gastric tumour and histopathology confirmed a pyloric gastric adenocarcinoma. Removal of the tumour via a Billroth I procedure resulted in rapid resolution of electrolyte derangements. The dog was still alive six months postoperatively with no recurrence of either SIADH or tumour at the time of publication.

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Citation topics
1 Clinical & Life Sciences
1.5 Neuroscience
1.5.941 Oxytocin and Vasopressin
Web Of Science research areas
Veterinary Sciences
ESI research areas
Plant & Animal Science
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