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Syndrome of inappropriate antidiuretic hormone secretion associated with congenital hydrocephalus in a dog
Journal article   Peer reviewed

Syndrome of inappropriate antidiuretic hormone secretion associated with congenital hydrocephalus in a dog

Robert E. Shiel, M. Pinilla and Carmel T. Mooney
The Journal of the American Animal Hospital Association, Vol.45(5), pp.249-252
2009
PMID: 19723849

Abstract

Animals Dog Diseases - blood Dog Diseases - diagnosis Dogs Drinking Hydrocephalus - blood Hydrocephalus - diagnosis Hydrocephalus - veterinary Inappropriate ADH Syndrome - blood Inappropriate ADH Syndrome - diagnosis Inappropriate ADH Syndrome - veterinary Magnetic Resonance Imaging - veterinary Male Osmolar Concentration Severity of Illness Index Syndrome Vasopressins - secretion
A 13-month-old, male bichon frise was examined for the investigation of intermittent seizures, ataxia, abnormal behavior, polyuria, and polydipsia. At presentation, clinical and neurological examinations were unremarkable with the exception of mild truncal ataxia and a domed skull. Severe hyponatremia and hypoosmolality were identified, and following diagnostic testing a diagnosis of the syndrome of inappropriate antidiuretic hormone secretion (SIADH) was made. Magnetic resonance imaging revealed changes consistent with severe hydrocephalus. Water restriction resulted in increased serum osmolality and a reduction in severity of clinical signs. The current case report documents SIADH associated with hydrocephalus in a dog. Structural brain disease should be excluded before a diagnosis of idiopathic SIADH is made.

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Citation topics
1 Clinical & Life Sciences
1.5 Neuroscience
1.5.941 Oxytocin and Vasopressin
Web Of Science research areas
Veterinary Sciences
ESI research areas
Plant & Animal Science
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