Journal article
Synthesis and acetylation of naphthols as precursors to naturally derived naphthoquinones; crystal structure of the aphin-related 7-O-methyl quinone A
Journal of the Chemical Society, Perkin Transactions 1, (8), pp.2459-2467
1988
Abstract
A route is described to 1,5,7-trialkoxy-4-naphthols. A method has been established to convert these compounds into the corresponding 3-acetyl-4-naphthols, in good yield, with a view to synthesizing naturally derived naphtho[2,3-c]pyran-5,10-quinones. Boron trichloride-induced monodemethylation of racemic Quinone A dimethyl ether was effected without perturbation of the pyran ring stereochemistry; this was confirmed by an X-ray crystallographic investigation.
Details
- Title
- Synthesis and acetylation of naphthols as precursors to naturally derived naphthoquinones; crystal structure of the aphin-related 7-O-methyl quinone A
- Authors/Creators
- R.G.F. Giles (Author/Creator)I.R. Green (Author/Creator)M.L. Niven (Author/Creator)S.C. Yorke (Author/Creator)
- Publication Details
- Journal of the Chemical Society, Perkin Transactions 1, (8), pp.2459-2467
- Publisher
- Royal Society of Chemistry
- Identifiers
- 991005545203507891
- Copyright
- © 1988 Royal Society of Chemistry
- Murdoch Affiliation
- Murdoch University
- Language
- English
- Resource Type
- Journal article
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