Journal article
Synthesis and physical properties of choline carboxylate ionic liquids
Journal of Chemical & Engineering Data, Vol.57(8), pp.2191-2196
2012
Abstract
A series of choline carboxylate ionic liquids (ILs) have been synthesized by neutralization of choline hydroxide solution with acetic, propanoic, butanoic, pivalic, and hexanoic acids. The salts so obtained were characterized by NMR spectroscopy, thermal methods, and elemental analysis. Key physical properties (density, viscosity, and refractive index) were measured for the propanoate, butanoate, and hexanoate salts at temperatures from (293.15 to 353.15) K. The densities were used to estimate the molecular volumes, standard entropies, crystal lattice energies, and thermal expansion coefficients. All five choline carboxylates were found to have cytotoxicities (IC50 values) above 10 mM toward the human breast cancer cell line, MCF-7, indicating they are much less toxic than common imidazolium-based ILs.
Details
- Title
- Synthesis and physical properties of choline carboxylate ionic liquids
- Authors/Creators
- N. Muhammad (Author/Creator) - Universiti Teknologi PetronasM.I. Hossain (Author/Creator)Z. Man (Author/Creator) - Universiti Teknologi PetronasM. El-Harbawi (Author/Creator) - Universiti Teknologi PetronasM.A. Bustam (Author/Creator) - Universiti Teknologi PetronasY.A. Noaman (Author/Creator) - Universiti Putra MalaysiaN.B. Mohamed Alitheen (Author/Creator)M.K. Ng (Author/Creator)G. Hefter (Author/Creator) - Murdoch UniversityC-Y Yin (Author/Creator) - Murdoch University
- Publication Details
- Journal of Chemical & Engineering Data, Vol.57(8), pp.2191-2196
- Publisher
- American Chemical Society
- Identifiers
- 991005543392607891
- Copyright
- © 2012 American Chemical Society
- Murdoch Affiliation
- School of Chemical and Mathematical Science
- Language
- English
- Resource Type
- Journal article
Metrics
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InCites Highlights
These are selected metrics from InCites Benchmarking & Analytics tool, related to this output
- Collaboration types
- Domestic collaboration
- International collaboration
- Citation topics
- 2 Chemistry
- 2.89 Ionic, Molecular & Complex Liquids
- 2.89.508 Ionic Liquids
- Web Of Science research areas
- Chemistry, Multidisciplinary
- Engineering, Chemical
- Thermodynamics
- ESI research areas
- Chemistry