Journal article
Synthesis of (1S)-N-(1-carboxy-5-aminopentyl)-glycylglycine - a prospective competitive inhibitor for angiotensin-converting enzyme
South African Journal of Chemistry, Vol.39(3), pp.134-136
1986
Abstract
The synthesis of a prospective competitive inhibitor of angiotensin-converting enzyme, (1 S )-N-(1-carboxy-5- aminopentyllglycylglycine (4), was accomplished in four steps in 72% overall yield starting from glycine. Hydrogenolysis of the benzyl and benzyloxycarbonyl protective groups in the last step was enhanced by the use of ultrasound.
Details
- Title
- Synthesis of (1S)-N-(1-carboxy-5-aminopentyl)-glycylglycine - a prospective competitive inhibitor for angiotensin-converting enzyme
- Authors/Creators
- S.C. Yorke (Author/Creator)M.R.W. Ehlers (Author/Creator)R.E. Kirsch (Author/Creator)R.G.F. Giles (Author/Creator)
- Publication Details
- South African Journal of Chemistry, Vol.39(3), pp.134-136
- Publisher
- South African Bureau for Scientific Publications
- Identifiers
- 991005544484807891
- Copyright
- © 1986 South African Chemical Institute (SACI)
- Murdoch Affiliation
- Murdoch University
- Language
- English
- Resource Type
- Journal article
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