Journal article
Synthesis of 2‐Acetyl‐4‐hydroxynaphtho[2,3‐b]pyran‐5,10‐dione and the 4‐Deoxy analogue as models for comparative biological evaluations
Synthetic Communications, Vol.34(14), pp.2565-2573
2004
Abstract
Two deoxy analogues of the known antibiotic, erythrostominone, have been synthesised for comparative evaluations. It was found that both the 2‐acetyl and the 4‐hydroxy substituents in the pyran ring are vital for improved biological activity.
Details
- Title
- Synthesis of 2‐Acetyl‐4‐hydroxynaphtho[2,3‐b]pyran‐5,10‐dione and the 4‐Deoxy analogue as models for comparative biological evaluations
- Authors/Creators
- F. Ameer (Author/Creator)R.G.F. Giles (Author/Creator)I.R. Green (Author/Creator)V.I. Hugo (Author/Creator)Samir Patel (Author/Creator)René Pearce (Author/Creator)
- Publication Details
- Synthetic Communications, Vol.34(14), pp.2565-2573
- Publisher
- Taylor and Francis
- Identifiers
- 991005544654907891
- Murdoch Affiliation
- School of Engineering and Energy
- Language
- English
- Resource Type
- Journal article
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- Collaboration types
- Domestic collaboration
- International collaboration
- Citation topics
- 1 Clinical & Life Sciences
- 1.219 Cancer Drugs
- 1.219.1527 Naphthoquinone Derivatives
- Web Of Science research areas
- Chemistry, Organic
- ESI research areas
- Chemistry