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Synthesis of mono and Bis[60]fullerene-based dicationic peptoids
Journal article   Open access   Peer reviewed

Synthesis of mono and Bis[60]fullerene-based dicationic peptoids

S. Jennepalli, K.A. Hammer, T.V. Riley, S.G. Pyne and P.A. Keller
European Journal of Organic Chemistry, Vol.2015(1), pp.195-201
2015
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Abstract

Increasing numbers of biological applications of fullerenyl amino acids and their derivatives encouraged us to synthesise [60]fullerenyldihydropyrrole peptides, prepared from the coupling of mono- and bis[60]fullerenyldihydropyrrolecarboxylic acids 4, 5 and 41 with presynthesised peptides 13, 16, 24, 28, 29 and 46. The resulting hydrophobic scaffolded di- and tetra-cationic derivatives were tested against Staphylococcus aureus NCTC 6571 and Escherichia coli NCTC 10418. The synthesis, characterisation and biological results are discussed in this paper.

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Collaboration types
Domestic collaboration
Citation topics
2 Chemistry
2.76 2D Materials
2.76.532 Fullerene Chemistry
Web Of Science research areas
Chemistry, Organic
ESI research areas
Chemistry
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