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Synthesis of new semi-rigid chelating agents for samarium-153
Journal article   Peer reviewed

Synthesis of new semi-rigid chelating agents for samarium-153

A. Loussouarn, A. Ouadi, L. Morandeau, P. Remaud, R. Giles, J-F Gestin and J. Webb
Tetrahedron Letters, Vol.44(17), pp.3539-3541
2003
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Abstract

This study describes a simple, efficient synthesis pathway from trans-1,2-diaminocyclohexane that provides access to a new class of semi-rigid polyamine, polycarboxylic, and polyphosphonic ligands. The key steps in synthesis were the functionalisation (with an appropriate branching group) of a bisphosphonate diaminocyclohexane derivative and the introduction of methanephosphonic functions by a rarely used method.

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Collaboration types
Domestic collaboration
International collaboration
Citation topics
1 Clinical & Life Sciences
1.204 Molecular & Cell Biology - Immunotherapy
1.204.1095 Radioimmunotherapy
Web Of Science research areas
Chemistry, Organic
ESI research areas
Chemistry
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