Journal article
Synthesis of selenomethylene-locked nucleic acid (SeLNA)-modified oligonucleotides by polymerases
Chemical Communications, Vol.48(89), pp.11020-11022
2012
Abstract
Enzymatic recognition of SeLNA nucleotides was investigated. KOD XL DNA polymerase was found to be an efficient enzyme in primer extension reactions. Polymerase chain reaction (PCR) amplification of SeLNA-modified DNA templates was also efficiently achieved by Phusion and KOD XL DNA polymerases.
Details
- Title
- Synthesis of selenomethylene-locked nucleic acid (SeLNA)-modified oligonucleotides by polymerases
- Authors/Creators
- M. Wheeler (Author/Creator) - The University of QueenslandA. Chardon (Author/Creator) - The University of QueenslandA. Goubet (Author/Creator) - The University of QueenslandK. Morihiro (Author/Creator) - The University of OsakaS.Y. Tsan (Author/Creator) - The University of QueenslandS.L. Edwards (Author/Creator) - The University of QueenslandT. Kodama (Author/Creator) - Nagoya UniversityS. Obika (Author/Creator) - The University of OsakaR.N. Veedu (Author/Creator) - The University of Queensland
- Publication Details
- Chemical Communications, Vol.48(89), pp.11020-11022
- Publisher
- Royal Society of Chemistry
- Identifiers
- 991005540769007891
- Copyright
- 2012 The Royal Society of Chemistry
- Murdoch Affiliation
- Murdoch University
- Language
- English
- Resource Type
- Journal article
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