Logo image
The E2C mechanism in elimination reactions. IX. Re-examination of the olefin-like transition-state
Journal article   Peer reviewed

The E2C mechanism in elimination reactions. IX. Re-examination of the olefin-like transition-state

D.M. Muir and A.J. Parker
Australian Journal of Chemistry, Vol.36(9), pp.1667-1673
1983
url
Link to Published Version *Subscription may be requiredView

Abstract

The kinetics and product olefins arising from E2C-like elimination reactions of secondary bromides and tosylates having various alkyl and conjugating substituents at Cα and Cβ are re-examined in the light of the theoretical Pross-Shaik valence-bond model and the apparent lack of a β-phenyl effect. Comparison of the effect of substituents at Cα and Cβ shows that whilst there are differences in reactivity and products of E2C reactions there is also a large degree of double-bond character in the transition state. There is a good correlation between the kinetics of E2C reactions and the double-bond stabilization energy arising from both alkyl and conjugating substituents. Contributing valence-bond structures, giving asymmetry and partial charge at Cα and Cβ appear to vary in importance according to leaving group and substituent type.

Details

UN Sustainable Development Goals (SDGs)

This output has contributed to the advancement of the following goals:

#3 Good Health and Well-Being

Source: InCites

Metrics

InCites Highlights

These are selected metrics from InCites Benchmarking & Analytics tool, related to this output

Citation topics
2 Chemistry
2.1 Synthesis
2.1.824 Solvolysis
Web Of Science research areas
Chemistry, Multidisciplinary
ESI research areas
Chemistry
Logo image