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The actionability of physical activity guidelines for multiple sclerosis care: a systematic review and AACTT framework analysis
Journal article   Open access   Peer reviewed

The actionability of physical activity guidelines for multiple sclerosis care: a systematic review and AACTT framework analysis

Claudia H Marck, Isabelle V Weld-Blundell, Marlena Klaic, Robert W Motl and Yvonne C Learmonth
Archives of physical medicine and rehabilitation
2024
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Abstract

clinical guidelines evidence translation exercise implementation science Multiple sclerosis physical activity rehabilitation systematic review
Objectives To conduct a systematic review of clinical guidelines, guidance documents and consensus statements regarding physical activity (PA) promotion by healthcare providers (HCPs) to people with multiple sclerosis (MS), and to assess the methodological quality, and actionability of the recommendations. The protocol was registered with Prospero (CRD42023495137). Data sources Clinical guidelines, guidance documents and consensus statements (hereafter guidelines) published in English between 2013-2023 were identified through extensive grey and scientific literature searches, and through contacting relevant HCP organisations in English speaking countries. Study Selection Two researchers independently screened titles and abstracts of the 939 identified records and included 19 guidelines which were developed for PA promotion as part of MS clinical management, and for which the target user was HCPs. Data Extraction Two researchers independently extracted data and appraised the methodological quality using the Appraisal of Guidelines for Research and Evaluation (AGREE-II). Behavioural actionability was analysed using the Actor, Action, Context, Target and Time (AACTT) framework. Data synthesis Seventy-eight recommendations from 19 guidelines were identified. Two guidelines had high methodological quality. Actor, Action, Context, Target and Time was clearly specified in 57 (73%), 45 (58%), 0 (0%), 51 (65%), and 24 (31%) of the 78 recommendations, respectively. Guidelines with the highest methodological quality did not always score well on actionability, and vice-versa. Conclusions Our comprehensive analysis of guidelines for PA promotion in MS reveals the need for more actionable recommendations and better reporting of guideline development, which has the potential to improve the translation of evidence into practice.

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