Files and links (1)
Published (Version of Record)CC BY-NC V4.0, Open Access
Journal article
The challenges of detecting Taenia solium and neurocysticercosis in low and middle‐income countries: A scoping review of Lao People's Democratic Republic
Tropical medicine & international health, Vol.28(5), pp.344-356
2023
PMID: 36898844
Appears in Open Access via Read & Publish Agreements
Abstract
Objective
Taenia solium is a tapeworm of global importance due to the burden of disease associated with human epilepsy caused by neurocysticercosis. Unfortunately, diagnostic challenges impede control efforts in many low and middle-income countries. This review examines publications concerning Taenia species in the Lao PDR with a focus on T. solium to inform future research and control programmes.
Methods
PubMed and Scopus databases were primary sources of evidence. Publications must have reported taeniasis or T. solium results from Lao PDR. Publications repeating results or samples were combined into unique projects.
Results
A total of 64 publications were included and summarised into 46 projects. The majority of projects applied faecal microscopy as their only diagnostic technique. As a result, the specific species of Taenia was often not determined. Only five projects used molecular techniques to identify the species observed. Only case report of neurocysticercosis has been published. The northern region was included in half the number of projects compared to the south, despite being a high-risk area T. solium.
Conclusions
The diagnostic challenge of determining the species of Taenia present in a faecal sample presents a significant limitation to the control of T. solium in Lao PDR and is an experience that is relevant to many other low and middle-income countries. There must be an improved understanding of the distribution and frequency of T. solium if disease control efforts are to be intensified to reduce the burden of neurocysticercosis, as encouraged by WHO and others. It is hoped that this can be achieved through non-biological risk mapping tools and the more frequent application of molecular tools to routine sample collection. Diagnostic tools that are applicable to low resource settings should be a priority area of research for T. solium.
Details
- Title
- The challenges of detecting Taenia solium and neurocysticercosis in low and middle‐income countries: A scoping review of Lao People's Democratic Republic
- Authors/Creators
- Andrew Larkins - Murdoch UniversitySarah Keatley - Murdoch UniversityBounnaloth Insisiengmay - Ministry of HealthRattanaxay Phetsouvanh - Ministry of HealthMieghan Bruce - Murdoch UniversityAmanda Ash - Murdoch University
- Publication Details
- Tropical medicine & international health, Vol.28(5), pp.344-356
- Publisher
- John Wiley & Sons Ltd.
- Number of pages
- 13
- Grant note
- Murdoch University Strategic Scholarship LS/2014/055 Australian Centre for International Agricultural Research
- Identifiers
- 991005578643407891
- Copyright
- © 2023 The Authors
- Murdoch Affiliation
- Centre for Biosecurity and One Health; School of Medical, Molecular and Forensic Sciences; School of Veterinary Medicine
- Language
- English
- Resource Type
- Journal article
UN Sustainable Development Goals (SDGs)
This output has contributed to the advancement of the following goals:
Source: InCites
Metrics
100 File views/ downloads
71 Record Views
InCites Highlights
These are selected metrics from InCites Benchmarking & Analytics tool, related to this output
- Collaboration types
- International collaboration
- Citation topics
- 1 Clinical & Life Sciences
- 1.163 Parasitology - General
- 1.163.1106 Echinococcosis
- Web Of Science research areas
- Public, Environmental & Occupational Health
- Tropical Medicine
- ESI research areas
- Social Sciences, general