The diversity and zoonotic potential of Staphylococcus pseudintermedius in humans and pet dogs in Trinidad and Tobago

Sharianne Suepaul; Marc Stegger; Filip Boyen; Karla Georges; Patrick Butaye

doi:10.3390/antibiotics12081266

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The diversity and zoonotic potential of Staphylococcus pseudintermedius in humans and pet dogs in Trinidad and Tobago

Journal article

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Peer reviewed

The diversity and zoonotic potential of Staphylococcus pseudintermedius in humans and pet dogs in Trinidad and Tobago

Sharianne Suepaul, Marc Stegger, Filip Boyen, Karla Georges and Patrick Butaye

Antibiotics (Basel), Vol.12(8), 1266

2023

DOI: https://doi.org/10.3390/antibiotics12081266

PMID: 37627686

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Abstract

Staphylococcus pseudintermedius is an opportunistic pathogen that is frequently isolated from canines. It is of escalating interest because of its increasing antimicrobial resistance and zoonotic potential. Although many published articles are available that describe isolates obtained from diseased dogs and humans, this study focused on isolates obtained from healthy dogs and their owners who presented at clinics for routine veterinary care and utilized whole genome sequencing-based analyses for strain comparisons. A total of 25 humans and 27 canines were sampled at multiple sites, yielding 47 and 45 isolates, respectively. Whole genome sequence analysis was performed. We detected mostly new sequence types (STs) and a high diversity. Strains carried few antimicrobial resistance genes and plasmids, albeit three MRSP strains were found that belonged to two internationally distributed STs. The virulence content did not provide insights toward a tendency to colonization of humans but supported that there may be differences in the surface proteins between carrier strains and those causing pyoderma. We identified 13 cases in which humans were infected with strains from the dog they owned.

Details

Title: The diversity and zoonotic potential of Staphylococcus pseudintermedius in humans and pet dogs in Trinidad and Tobago
Authors/Creators: Sharianne Suepaul - University of the West Indies
Marc Stegger
Filip Boyen - Ghent University
Karla Georges - University of the West Indies
Patrick Butaye - Ghent University
Publication Details: Antibiotics (Basel), Vol.12(8), 1266
Publisher: MDPI
Grant note: CRP.3.MAR16.36 / University of the West Indies Campus Research and Publication Fund G0H2516N; AUGE/15/05 / Research Foundation Flanders (FWO-Vlaanderen) 22/001 / Ross University School of Veterinary Medicine
Identifiers: 991005601368907891
Copyright: © 2023 by the authors.
Murdoch Affiliation: Harry Butler Institute
Language: English
Resource Type: Journal article

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Collaboration types: Domestic collaboration; International collaboration
Citation topics: 1 Clinical & Life Sciences; 1.23 Antibiotics & Antimicrobials; 1.23.173 MRSA and VRE
Web Of Science research areas: Infectious Diseases; Pharmacology & Pharmacy
ESI research areas: Pharmacology & Toxicology