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The effect of comorbidities on risk of intensive care readmission during the same hospitalization: A linked data cohort study
Journal article   Peer reviewed

The effect of comorbidities on risk of intensive care readmission during the same hospitalization: A linked data cohort study

K.M. Ho, G.J. Dobb, K.Y. Lee, J. Finn, M.W. Knuiman and S.A.R. Webb
Journal of Critical Care, Vol.24(1), pp.101-107
2009
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Abstract

Purpose: The aim of this study is to assess the effect of comorbidities on risk of readmission to an intensive care unit (ICU) and the excess hospital mortality associated with ICU readmissions. Materials and Methods: A cohort study used clinical data from a 22-bed multidisciplinary ICU in a university hospital and comorbidity data from the Western Australian hospital morbidity database. Results: From 16 926 consecutive ICU admissions between 1987 and 2002, and 654 (3.9%) of these patients were readmitted to ICU readmissions within the same hospitalization. Patients with readmission were older, more likely to be originally admitted from the operating theatre or hospital ward, had a higher Acute Physiology and Chronic Health Evaluation (APACHE)-predicted mortality, and had more comorbidities when compared with patients without readmission. The number of Charlson comorbidities was significantly associated with late readmission (>72 hours) but not early readmission (≤72 hours) in the multivariate analysis. Both early and late ICU readmissions were associated with an increased risk of hospital mortality (odds ratio, 1.68; 95% confidence interval, 1.18-2.39; P = .004; odds ratio, 1.45; 95% confidence interval, 1.05-1.99; P = .022, respectively) after adjusting for age, admission source, type of admission, the APACHE-predicted mortality, and the number of Charlson comorbidities and APACHE chronic health conditions. Conclusions: Comorbidity was a risk factor for late ICU readmission. Comorbidities could not account for the excess mortality associated with ICU readmissions.

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Collaboration types
Domestic collaboration
Citation topics
1 Clinical & Life Sciences
1.154 Assisted Ventilation
1.154.1088 Intensive Care
Web Of Science research areas
Critical Care Medicine
ESI research areas
Clinical Medicine
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