Journal article
The effect of exercise on lymphocyte redistribution and leucocyte function in asymptomatic HIV-Infected subjects
Brain, Behavior, and Immunity, Vol.11(3), pp.217-227
1997
Abstract
This study was undertaken to examine the responsiveness of circulating leucocyte and lymphocyte populations to the physiological demands of exercise in asymptomatic HIV-infected subjects with CD4+ counts greater than 500/μl. Thirteen subjects infected with HIV and 14 control subjects underwent 20 min of defined moderate exercise at estimated 65% of their maximal ventilatory capacity on a bicycle ergometer. Blood samples were obtained for serum cortisol, norepinephrine, lymphocyte subsets (CD4, CD8, CD19, CD16–CD56), and phagocytic function at rest immediately after exercise and 20 min following the cessation of the exercise. The HIV-infected subjects had increased circulating concentrations of CD8 cells (p= .007) and CD16–CD56+ NK cells (p= .02) in response to the exercise, whereas the control group did not. There was a greater increase in monocyte respiratory burst activity following recovery from exercise in the control subjects (p= .016) but not in the HIV-infected subjects. The control subjects experienced an increase in serum cortisol in response to the exercise (p= .006), but the HIV-infected subjects did not. Our results show that the changes in the distribution and function of circulating leucocytes and adrenal neuroendocrine responses to moderate exercise differ in asymptomatic HIV-infected and control subjects.
Details
- Title
- The effect of exercise on lymphocyte redistribution and leucocyte function in asymptomatic HIV-Infected subjects
- Authors/Creators
- E. Phillips (Author/Creator)
- Publication Details
- Brain, Behavior, and Immunity, Vol.11(3), pp.217-227
- Publisher
- Elsevier
- Identifiers
- 991005544675807891
- Copyright
- 1997 Academic Press
- Murdoch Affiliation
- Murdoch University
- Language
- English
- Resource Type
- Journal article
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- Citation topics
- 1 Clinical & Life Sciences
- 1.172 Sports Science
- 1.172.1542 Exercise Immunology
- Web Of Science research areas
- Immunology
- Neurosciences
- Psychiatry
- ESI research areas
- Neuroscience & Behavior