The effect of sodium monofluoroacetate on plasma testosterone concentration in Tiliqua rugosa (gray)

L.E. Twigg; D.R. King; A.J. Bradley

doi:10.1016/0742-8413(88)90040-0

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The effect of sodium monofluoroacetate on plasma testosterone concentration in Tiliqua rugosa (gray)

Journal article

Peer reviewed

The effect of sodium monofluoroacetate on plasma testosterone concentration in Tiliqua rugosa (gray)

L.E. Twigg, D.R. King and A.J. Bradley

Comparative Biochemistry and Physiology Part C: Comparative Pharmacology, Vol.91(2), pp.343-347

1988

DOI: https://doi.org/10.1016/0742-8413(88)90040-0

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Abstract

1. 1. Administration of multiple or single doses of sodium fluoroacetate (1080) to male Tiliqua rugosa caused a decrease in plasma testosterone concentration. 2. 2. A single dose of 100 or 250 mg 1080 kg-1 body weight decreased plasma testosterone by 52%. However, 25 mg kg-1 had little apparent effect on testosterone levels. When lizards were given the multiple dose equivalent of these doses over 12 days at 3 day intervals, the effect was much less dramatic with plasma testosterone concentration steadily declining over 15 days for the two higher doses. 3. 3. There was a suggestion of degeneration of seminiferous tubules in some individuals

Details

Title: The effect of sodium monofluoroacetate on plasma testosterone concentration in Tiliqua rugosa (gray)
Authors/Creators: L.E. Twigg (Author/Creator) - Murdoch University
D.R. King (Author/Creator) - Agriculture Protection Board, Bougainvillea Avenue, Forrestfield, Western Australia, 6058
A.J. Bradley (Author/Creator) - The University of Western Australia
Publication Details: Comparative Biochemistry and Physiology Part C: Comparative Pharmacology, Vol.91(2), pp.343-347
Publisher: Elsevier BV
Identifiers: 991005542106707891
Murdoch Affiliation: School of Environmental and Life Sciences
Language: English
Resource Type: Journal article

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Collaboration types: Domestic collaboration
Citation topics: 3 Agriculture, Environment & Ecology; 3.35 Zoology & Animal Ecology; 3.35.274 Wildlife Ecology
Web Of Science research areas: Biochemistry & Molecular Biology; Endocrinology & Metabolism; Toxicology; Zoology
ESI research areas: Biology & Biochemistry