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The influence of clinical evidence on surgical practice
Journal article   Peer reviewed

The influence of clinical evidence on surgical practice

S. Honeybul and K.M. Ho
Journal of Evaluation in Clinical Practice, Vol.19(5), pp.825-828
2013
DOI: https://doi.org/10.1111/j.1365-2753.2012.01857.x
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Abstract

Given the considerable interest in the use of evidence-based medicine to guide clinical practice, it is surprising that the results of a recent randomized controlled trial have been met with such a limited response. The DECompressive CRAniectomy study investigators have recently published the results of a landmark trial in neurosurgery, comparing early decompressive craniectomy with standard medical therapy in patients who developed intracranial hypertension after diffuse closed traumatic brain injury (TBI). This is the first ever randomized controlled trial investigating the surgical management of adult patients with severe TBI. The trial clearly demonstrated that early decompression did not provide clinical benefit; however, rather than having a significant impact on clinical practice, it has been almost uniformly criticized. While there were some problems with randomization and crossover, we feel that the trial has been somewhat misinterpreted and in this article we address some of the key issues.

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UN Sustainable Development Goals (SDGs)

This output has contributed to the advancement of the following goals:

#3 Good Health and Well-Being

Source: InCites

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23 Record Views
1 Times Cited - Web of Science

InCites Highlights

These are selected metrics from InCites Benchmarking & Analytics tool, related to this output

Collaboration types
Domestic collaboration
Citation topics
1 Clinical & Life Sciences
1.134 Trauma & Emergency Surgery
1.134.286 Traumatic Brain Injury
Web Of Science research areas
Health Care Sciences & Services
Medical Informatics
ESI research areas
Clinical Medicine
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